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Philip R Hardwidge


Philip R Hardwidge

Kansas State University, USA

Biography

Philip R Hardwidge is an Associate Professor at Kansas State University. His laboratory is interested in understanding, treating and preventing diarrheal disease caused by bacterial pathogens. His research team has discovered several mechanisms by which bacterial proteins subvert the host innate immune system to promote bacterial colonization and transmission. He is directing his knowledge of these proteins and their mammalian targets to innovative studies of metabolic syndromes, autoimmune disorders and cancer. He is also developing proteomic techniques to identify vaccine targets in other organisms.

Abstract

Abstract : Citrobacter rodentium NleB blocks TRAF3 K63-linked ubiquitination to inhibit interferon-β production