Species Immunity

Bacteria, and possibly other prokaryotic organisms, employ a unique defense mechanism known as the restriction-modification (R-M) system to protect themselves from viral pathogens such as bacteriophages. In this system, bacteria produce specialized enzymes called restriction endonucleases that recognize and cleave specific sequences within the viral DNA, thereby neutralizing the invading threat. To avoid self-damage, the bacterial host marks its own DNA through methylation, which designates it as "self" and prevents cleavage by its own endonucleases. Notably, both restriction endonucleases and the R-M system are exclusive to prokaryotes, representing a fundamental microbial immune strategy.

In contrast, invertebrates lack lymphocytes and an antibody-mediated humoral immune system, suggesting that a complex, multicomponent adaptive immune system likely evolved with the emergence of vertebrates. Despite this, invertebrates possess innate immune mechanisms that appear to be evolutionary precursors to aspects of vertebrate immunity.

One such mechanism involves pattern recognition receptors (PRRs) proteins found in nearly all organisms that detect pathogen-associated molecular patterns (PAMPs). A major class of PRRs is the Toll-like receptors (TLRs), which are present in all coelomates (animals with a body cavity), including humans, and play a central role in initiating immune responses upon pathogen detection.

Additionally, many forms of life, including invertebrates, possess a complement-like system. While vertebrates rely on a fully developed complement cascade to clear pathogens, some invertebrates such as insects, crabs, and worms employ a modified version called the prophenoloxidase (proPO) system. This system participates in immune defense through processes like melanization, which encapsulates and neutralizes pathogens.

 

    Related Conference of Species Immunity

    September 22-23, 2025

    21st Global Biomarkers and Clinical Research Summit

    Paris, France
    September 25-26, 2025

    3rd International Conference on Oral Health and Dentistry

    Zurich, Switzerland
    October 27-28, 2025

    10th Global Summit on Midwifery and Womens Health

    Madrid, Spain
    October 30-31, 2025

    6th International Conferences in COPD & Lung Disease

    Paris, France
    November 13-14, 2025

    5th Euro-Global Summit on Probiotics & Nutraceuticals

    Paris, France
    November 13-14, 2025

    11th World Holistic Nursing Conference

    Bali, Indonesia
    November 20-21, 2025

    6th Global Summit on Public Health

    Amsterdam, Netherlands
    November 24-25, 2025

    4th Global Conference on Aging and Gerontology

    Barcelona, Spain
    November 24-25, 2025

    11th Global Public Health, Occupational Safety and Health Policy

    Aix-en-Provence, France
    December 04-05, 2025

    Innateimmunity

    Dubai, UAE
    December 17-18, 2025

    8th Annual Congress on Wellness and Alternative Healthcare Informatics

    Aix-en-Provence, France
    December 17-18, 2025

    12th World congress on Hospice and Palliative care

    Aix-en-Provence, France
    December 29-30, 2025

    13th International Conference on Hospital Management and Health Care

    Amsterdam, Netherlands
    January 28-29, 2026

    43rd International Conference on Women's Health

    Bangkok, Thailand
    February 16-17, 2026

    11th World Congress on Public Health and Nutrition

    Paris, France
    March 12-13, 2026

    8th International Conference on Digital Health

    London, UK
    April 08-09, 2026

    5th International Congress on Global Healthcare

    Vienna, Austria
    April 20-21, 2026

    7th Global Summit on Digital Therapeutics

    Barcelona, Spain
    April 27-28, 2026

    8th World Summit on Women's Health and Cancer Awareness

    Vancouver, Canada
    June 01-02, 2026

    2nd International Congress on Primary Health and Safety

    Zurich, Switzerland
    June 15-16, 2026

    6th International conference on Healthcare Summit

    Paris, France
    June 15-16, 2026

    8th World Conference on Vaccine and Immunology

    Paris, France
    July 23-24, 2026

    37th European Heart and Heart Failure Congress

    Aix-en-Provence, France

    Species Immunity Conference Speakers

      Recommended Sessions

      Related Journals

      Are you interested in